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PHARMACEUTICALS |
IUPAC Name: Benzene-1,2-diol
Synonym: Pyrocatechol 1,2-Benzenediol, 2-Hydroxyphenol, 1,2-Dihydroxybenzene, o-Benzenediol, o-Dihydroxybenzene
CAS no :120-80-9
EEC no :204-427-5
Molecular Formula: C6H6O2
Molecular Weight: 110.11g/mol
Catechol, also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound with the molecular formula C6H4(OH)2. It is the ortho isomer of the three isomeric benzenediols. Catechol is available as flakes and 85% solution in solvents. It is produced industrially by the hydroxylation of phenol using hydrogen peroxide.
C6H5OH + H2O2 → C6H4(OH)2 + H2O
Applications:
- Used largely in the production of pesticides
-Used as a precursor to fine chemicals such as perfumes and pharmaceuticals.
- Several flavours and fragrances are prepared starting from catechol.
- Piperonal, a flowery scent, is prepared from the methylene diether of catechol
- Vanillin, a flavour and fragrance component is synthetically produced using Catechol. CFS uses environment-friendly process to manufacture it. Vanillin produced through this route is safe for food applications.
- Used in production of ethylvanillin, a component of chocolate confectioneries.
- Used for replacing sandalwood oil
- Guaiacol is prepared by methylation of catechol
1,4-Dimethoxybenzene (PDMB) is obtained from hydroquinone and is a solid crystalline mass, white in colour with pleasant sweet odour. It is used in synthesis of the active pharmaceutical ingredient Medodrine. It is manufactured industrially by the methylation of hydroquinone.
Applications:
Used in industry as an intermediate for fine chemical synthesis or an ingredient in the formulation of perfumes, cosmetics, personal care products, detergents (washing and cleaning products) and flavouring agents.
Used in dyes (yellow pigment).
Used as a weathering agent in paints and dyes
Name: Veratrole
Chemical Name: 1,2-Dimethoxybenzene
Synonym: Pyrocatechol dimethyl ether ortho-Dimethoxybenzene
Cas no.: 91-16-7
Molecular Formula: C8H10O2
Molecular Weight:138.16 g/mol
Veratrole is a clear colourless liquid (above 22°C). Veratrole is manufactured in industry by methylation of pyrocatechol and used as a precursor for the synthesis of active pharmaceutical ingredients, flavouring agents and perfumery products.
Applications
Used as a building block for various chemical compounds, some of it are as follows:
Agrochemical: Used in the synthesis of fungicide Dimethomorph.
Flavours & Fragrances: Used in the synthesis of flavours and fragrances such as Veratraldehyde, 4-Ethyl veratrole and 4-Propenyl veratrole etc.
Active Pharmaceutical Ingredients: Intermediates prepared from Veratrole are used in the synthesis of various active pharmaceutical ingredients such as Verapamil, Mebevarine, Papevarine, Donepezil & Itopride etc.
Name: Guethol
Chemical Name: 2-Ethoxyphenol
Synonym: o-Ethoxyphenol
Cas no.: 94-71-3
Molecular Formula: C8H10O2
Molecular Weight: 138.166 g/mol
Guethol is an aromatic ether in which one of the hydroxy groups has been alkylated to give the corresponding ethyl ether. It is a volatile organic compound and a member of phenols. It derives from a catechol and has a role as a flavouring agent.
Name: Para-Benzoquinone (PBQ)
Chemical Name: 1,4-Benzoquinone
Synonym: p-Dioxobenzene p-Quinonee
Cas no.: 106-51-4
Molecular Formula: C8H4O2
Molecular Weight: 108.1 g/mol
Para-Benzoquinone is an organic chemical compound commonly known as p-Quinone. It is a bright yellow to light brown coloured crystalline solid with a strong pungent, irritating odour. It is manufactured by the oxidation of hydroquinone. It is used as a polymerization inhibitor and as an intermediate in the production of a variety of substances including rubber accelerators and oxidizing agents.
PBQ is able to stain skin dark brown, cause erythema (redness, rashes on skin) and lead to a localized tissue necrosis.
APPLICATION:
Para-Benzoquinone acts as a cross linking agent and is useful in stabilizing unsaturated polyester resins during processing, shipment, and storage in either catalyzed or per catalyzed form.
Used as a chemical intermediate for the manufacture of the agrochemical herbicide, Ethofumesate and the active pharmaceutical ingredient, Calcium dobesilate.
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