HEALTH & WELLBEING

IUPAC Name :2-Methoxyphenol
Synonym: Pyrocatechol monomethyl ether 1-Hydroxy-2-methoxybenzene
CAS no.: 90-05-1
Molecular Formula: C7H8O2
Molecular Weight:124.14 g/mol

Guaiacol is a naturally occurring organic compound, known for its flavouring properties. It is clear colourless to slightly yellow coloured liquid (above 28°C) or crystalline solid mass with characteristic aromatic odour.

Guaiacol is manufactured in industry by methylation of pyrocatechol and mainly used as a precursor for synthesis of Vanillin. It is also used in synthesis of active pharmaceutical ingredients, flavouring agents and perfumery products.

APPLICATION:

Flavours & Fragrances:
Guaiacol is used in the synthesis of various flavours and fragrances such as Vanillin, Isovanillin, Eugenol, Isoeugenol, Zingerone, 4-Ethylguaiacol & 4-Vinylguaiacol etc.

Active Pharmaceutical Ingredients:
Guaiacol is used in the synthesis of expectorant such as Guaifenesin and Sulfoguaiacol. Drug intermediates obtained from Guaiacol are used in the synthesis of muscle relaxant and cardio vascular drugs such as Methacarbamol, Carvedilol and Ranolazine.

HYDROQUINONE (Photographic Grade)
IUPAC name : Benzene-1,4-diol
Other names : Hydroquinone, Idrochinone, Quinol , 1,4-Dihydroxybenzene , 1,4-Hydroxy benzene
CAS no :123-31-9
EEC no :204-617-8
Molecular Formula :C6H6O2
Molecular Weight :110.11g/mol

Hydroquinone is an aromatic organic compound that is a type of phenol, and a derivative of benzene. It is available as a white granular solid.

Hydroquinone is produced industrially by two main routes. The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene. This compound reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges to give acetone and hydroquinone in acid. A second route involves hydroxylation of phenol. The conversion uses hydrogen peroxide and affords a mixture of hydroquinone and catechol:

C6H5OH + H2O2 → C6H4(OH)2 + H2O

CATECHOL
IUPAC Name: Benzene-1,2-diol
Synonym: Pyrocatechol 1,2-Benzenediol, 2-Hydroxyphenol, 1,2-Dihydroxybenzene, o-Benzenediol, o-Dihydroxybenzene
CAS no :120-80-9
EEC no :204-427-5
Molecular Formula: C6H6O2
Molecular Weight: 110.11g/mol

Catechol, also known as pyrocatechol or 1,2-dihydroxybenzene, is an organic compound with the molecular formula C6H4(OH)2. It is the ortho isomer of the three isomeric benzenediols. Catechol is available as flakes and 85% solution in solvents. It is produced industrially by the hydroxylation of phenol using hydrogen peroxide.

C6H5OH + H2O2 → C6H4(OH)2 + H2O

Applications:
- Used largely in the production of pesticides
-Used as a precursor to fine chemicals such as perfumes and pharmaceuticals.
- Several flavours and fragrances are prepared starting from catechol.
- Piperonal, a flowery scent, is prepared from the methylene diether of catechol
- Vanillin, a flavour and fragrance component is synthetically produced using Catechol. CFS uses environment-friendly process to manufacture it. Vanillin produced through this route is safe for food applications.
- Used in production of ethylvanillin, a component of chocolate confectioneries.
- Used for replacing sandalwood oil
- Guaiacol is prepared by methylation of catechol

Name: Veratrole
Chemical Name: 1,2-Dimethoxybenzene
Synonym: Pyrocatechol dimethyl ether ortho-Dimethoxybenzene
Cas no.: 91-16-7
Molecular Formula: C8H10O2
Molecular Weight:138.16 g/mol

Veratrole is a clear colourless liquid (above 22°C). Veratrole is manufactured in industry by methylation of pyrocatechol and used as a precursor for the synthesis of active pharmaceutical ingredients, flavouring agents and perfumery products.

Applications
Used as a building block for various chemical compounds, some of it are as follows:

Agrochemical: Used in the synthesis of fungicide Dimethomorph.

Flavours & Fragrances: Used in the synthesis of flavours and fragrances such as Veratraldehyde, 4-Ethyl veratrole and 4-Propenyl veratrole etc.

Active Pharmaceutical Ingredients: Intermediates prepared from Veratrole are used in the synthesis of various active pharmaceutical ingredients such as Verapamil, Mebevarine, Papevarine, Donepezil & Itopride etc.

Name: Guethol
Chemical Name: 2-Ethoxyphenol
Synonym: o-Ethoxyphenol
Cas no.: 94-71-3
Molecular Formula: C8H10O2
Molecular Weight: 138.166 g/mol

Guethol is an aromatic ether in which one of the hydroxy groups has been alkylated to give the corresponding ethyl ether. It is a volatile organic compound and a member of phenols. It derives from a catechol and has a role as a flavouring agent.

1,2-Diethoxybenzene (ODEB)
IUPAC Name: 1,2-Diethoxybenzene
Synonym: Pyrocatechol diethyl ether ortho-Diethoxybenzene
Cas no.: 2050-46-6
Molecular Formula: C10H14O2
Molecular Weight: 166.22 g/mol

ODEB (1,2-Diethoxybenzene) is colourless crystalline solid (below 40°C) with a phenol like odour.

ODEB is manufactured industrially by the ethylation of pyrocatechol and used as a precursor for the synthesis of active pharmaceutical ingredients and agrochemical products.


Applications:
Used as a building block for various chemical compounds, some of it are as follows:

Intermediates prepared from ODEB are used in the synthesis of active pharmaceutical ingredient such as Drotaverine.

Its intermediates are also used in the manufacture of antiprotozoal veterinary drug, Decoquinate.

Used as a key raw material in the manufacture of the agrochemical fungicide, Diethofencarb.

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